Tocris/CGP 13501/1514/50/50 mg
Description: Positive modulator at GABAB receptors
Chemical Name: 3,5-bis(1,1-Dimethylethyl)-4-hydroxy-α,α-dimethylbenzenepropanal
Purity: ≥98% (HPLC)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

Positive allosteric modulator of GABAB receptors, potentiating the effects of GABA at this receptor type.

Technical Data

M. Wt 290.44
Formula C19H30O2
Storage Desiccate at +4°C
Purity ≥98% (HPLC)
CAS Number 56189-68-5
PubChem ID 3519541
InChI Key XGWATTXMMMANFJ-UHFFFAOYSA-N
Smiles CC(C)(C)C1=CC(CC(C)(C)C=O)=CC(=C1O)C(C)(C)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 29.04 100
ethanol 29.04 100

Preparing Stock Solutions

The following data is based on the product Molecular weight 290.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.44 mL 17.22 mL 34.43 mL
5 mM 0.69 mL 3.44 mL 6.89 mL
10 mM 0.34 mL 1.72 mL 3.44 mL
50 mM 0.07 mL 0.34 mL 0.69 mL

Product Datasheets

Certificate of Analysis / Product Datasheet
Safety Datasheet

References

References are publications that support the products' biological activity.

Urwyler et al (2001) Positive allosteric modulation of native and recombinant γ-aminobutyric acidB receptors by 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol.Pharmacol. 60 963 PMID: 11641424


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